Getting hit by SUMO
نویسندگان
چکیده
منابع مشابه
SUMO: getting it on.
Post-translational modification of cellular proteins by the SUMO (small ubiquitin-related modifier) is involved in numerous modes of regulation in widely different biological processes. In contrast with ubiquitination, SUMO conjugation is highly specific in terms of target lysine residues, but many aspects of substrate and lysine selection by the SUMO conjugating machinery are still poorly unde...
متن کاملProtein modification by SUMO.
Small ubiquitin-related modifier (SUMO) family proteins function by becoming covalently attached to other proteins as post-translational modifications. SUMO modifies many proteins that participate in diverse cellular processes, including transcriptional regulation, nuclear transport, maintenance of genome integrity, and signal transduction. Reversible attachment of SUMO is controlled by an enzy...
متن کاملPost-translational modification by SUMO.
Post-translational modifications (PTMs) are chemical alterations to a protein following translation, regulating stability and function. Reversible phosphorylation is an example of an important and well studied PTM involved in a number of cellular processes. SUMOylation is another PTM known to modify a large number of proteins and plays a role in various cellular processes including: cell cycle ...
متن کاملSumo
believes philosophical investigations are neither superior to, or prior to, investigations in the natural sciences. Concern about free will is one of the key issues behind most of the resistance to materialism generally and neo-Darwinism in particular, he says. Dennett spells out just how the process of natural selection can generate organisms with greater choice in their actions. " We are now ...
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ne wo (E hospital ma O of the key issues for high-volume, high-risk rkplaces like hospital emergency departments Ds) is the struggle of conflicting aims. While nagers need information systems for data collection and storage, clinicians need efficient clinical documentation, data retrieval and order-entry systems that save time rather than steal it from the patient. The work of clinicians is aid...
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ژورنال
عنوان ژورنال: Nature Cell Biology
سال: 2002
ISSN: 1465-7392,1476-4679
DOI: 10.1038/ncb0302-e57